| Gilead Sciences(GILD.US) | 9.40 | 5,566,313 |
| Vertex Pharmaceuticals(VRTX.US) | 9.10 | 1,615,426 |
| Amgen Inc.(AMGN.US) | 8.92 | 2,027,628 |
| Regeneron Pharmaceuticals(REGN.US) | 6.71 | 757,075 |
| Alnylam Pharmaceuticals(ALNY.US) | 3.66 | 970,841 |
| Insmed(INSM.US) | 2.66 | 1,573,464 |
| argenx(ARGX.US) | 2.63 | 302,813 |
| Biogen(BIIB.US) | 2.38 | 1,095,699 |
| Natera(NTRA.US) | 2.32 | 982,644 |
| BeOne Medicines(ONC.US) | 1.94 | 540,977 |
| United Therapeutics(UTHR.US) | 1.78 | 310,759 |
| Illumina(ILMN.US) | 1.69 | 1,111,153 |
| Incyte(INCY.US) | 1.67 | 1,452,871 |
| Moderna(MRNA.US) | 1.58 | 2,593,110 |
| Revolution Medicines(RVMD.US) | 1.43 | 1,236,751 |
| Genmab(GMAB.US) | 1.23 | 3,678,756 |
| Ionis Pharmaceuticals(IONS.US) | 1.09 | 1,188,451 |
| Neurocrine Biosciences(NBIX.US) | 1.09 | 726,308 |
| Roivant Sciences(ROIV.US) | 1.06 | 3,237,539 |
| BioMarin(BMRN.US) | 0.99 | 1,416,296 |
| Exelixis(EXEL.US) | 0.97 | 1,942,694 |
| BridgeBio Pharma(BBIO.US) | 0.93 | 1,231,056 |
| Ascendis Pharma(ASND.US) | 0.92 | 346,606 |
| Medpace Holdings(MEDP.US) | 0.87 | 169,060 |
| AVIDITY BIOSCIENCES INC | 0.84 | 1,015,522 |
| Bio-Techne(TECH.US) | 0.77 | 1,151,765 |
| Madrigal Pharmaceuticals(MDGL.US) | 0.76 | 154,324 |
| Charles River(CRL.US) | 0.74 | 363,925 |
| Praxis Precision Medicines(PRAX.US) | 0.73 | 190,767 |
| Halozyme Therapeutics(HALO.US) | 0.69 | 869,719 |
| Arrowhead Pharmaceuticals(ARWR.US) | 0.68 | 942,564 |
| Vaxcyte(PCVX.US) | 0.66 | 949,590 |
| BioNTech(BNTX.US) | 0.64 | 514,326 |
| Cytokinetics(CYTK.US) | 0.63 | 896,700 |
| Krystal Biotech(KRYS.US) | 0.58 | 186,068 |
| Repligen(RGEN.US) | 0.58 | 398,153 |
| Axsome Therapeutics(AXSM.US) | 0.57 | 309,247 |
| Abivax(ABVX.US) | 0.54 | 394,519 |
| Rhythm Pharmaceuticals(RYTM.US) | 0.49 | 466,397 |
| CRISPR Therapeutics(CRSP.US) | 0.47 | 683,617 |
| Kymera Therapeutics(KYMR.US) | 0.46 | 445,921 |
| Protagonist Therapeutics(PTGX.US) | 0.46 | 442,229 |
| Tempus(TEM.US) | 0.46 | 761,713 |
| PTC Therapeutics(PTCT.US) | 0.45 | 577,317 |
| Arcellx(ACLX.US) | 0.42 | 323,561 |
| Nuvalent(NUVL.US) | 0.41 | 358,280 |
| Alkermes(ALKS.US) | 0.41 | 1,206,919 |
| Mirum Pharmaceuticals(MIRM.US) | 0.41 | 390,945 |
| Cogent Biosciences(COGT.US) | 0.41 | 919,879 |
| Amicus Therapeutics(FOLD.US) | 0.37 | 2,257,999 |
| Bruker(BRKR.US) | 0.35 | 771,263 |
| ACADIA Pharmaceuticals(ACAD.US) | 0.35 | 1,249,871 |
| Terns Pharmaceuticals(TERN.US) | 0.32 | 671,424 |
| Crinetics Pharmaceuticals(CRNX.US) | 0.31 | 660,781 |
| ADMA Biologics(ADMA.US) | 0.30 | 1,722,914 |
| Scholar Rock Holding(SRRK.US) | 0.30 | 593,255 |
| Apogee Therapeutics(APGE.US) | 0.28 | 356,874 |
| Structure Therapeutics(GPCR.US) | 0.28 | 394,788 |
| ImmunityBio(IBRX.US) | 0.27 | 2,475,013 |
| Xenon Pharmaceuticals(XENE.US) | 0.27 | 559,567 |
| Tarsus Pharmaceuticals(TARS.US) | 0.25 | 292,749 |
| Spyre Therapeutics(SYRE.US) | 0.25 | 504,971 |
| Arcutis Biotherapeutics(ARQT.US) | 0.25 | 805,561 |
| CG Oncology(CGON.US) | 0.24 | 365,511 |
| Veracyte(VCYT.US) | 0.24 | 578,653 |
| Denali Therapeutics(DNLI.US) | 0.23 | 975,896 |
| Twist Bioscience(TWST.US) | 0.23 | 433,068 |
| IDEAYA Biosciences(IDYA.US) | 0.23 | 627,062 |
| NewAmsterdam Pharma(NAMS.US) | 0.23 | 564,714 |
| Legend Biotech(LEGN.US) | 0.22 | 1,035,742 |
| Travere Therapeutics(TVTX.US) | 0.22 | 656,710 |
| Beam Therapeutics(BEAM.US) | 0.22 | 684,797 |
| 10x Genomics(TXG.US) | 0.22 | 836,533 |
| BLK CSH FND TREASURY SL AGENCY | 0.20 | 17,852,748 |
| Immunovant(IMVT.US) | 0.20 | 635,864 |
| Adaptive Biotechnologies(ADPT.US) | 0.20 | 1,095,442 |
| Caris Life Sciences(CAI.US) | 0.20 | 863,413 |
| Edgewise Therapeutics(EWTX.US) | 0.20 | 569,932 |
| Erasca(ERAS.US) | 0.18 | 1,193,581 |
| Apellis Pharmaceuticals(APLS.US) | 0.18 | 776,220 |
| Alumis(ALMS.US) | 0.18 | 540,421 |
| Ultragenyx Pharmaceutical(RARE.US) | 0.18 | 670,697 |
| BioCryst Pharmaceuticals(BCRX.US) | 0.17 | 1,702,757 |
| Vera Therapeutics(VERA.US) | 0.17 | 363,821 |
| Centessa Pharmaceuticals(CNTA.US) | 0.16 | 533,981 |
| WAVE Life Sciences(WVE.US) | 0.16 | 1,009,151 |
| Dyne Therapeutics(DYN.US) | 0.16 | 891,130 |
| Syndax Pharmaceuticals(SNDX.US) | 0.15 | 628,993 |
| GRAIL(GRAL.US) | 0.15 | 250,874 |
| Disc Medicine(IRON.US) | 0.15 | 200,072 |
| Vericel(VCEL.US) | 0.15 | 373,534 |
| Summit Therapeutics(SMMT.US) | 0.14 | 768,832 |
| Zymeworks(ZYME.US) | 0.14 | 544,624 |
| Aurinia Pharmaceuticals(AUPH.US) | 0.14 | 881,132 |
| Stoke Therapeutics(STOK.US) | 0.14 | 341,924 |
| Grifols(GRFS.US) | 0.14 | 1,365,919 |
| Definium Therapeutics(DFTX.US) | 0.14 | 711,830 |
| Agios Pharmaceuticals(AGIO.US) | 0.14 | 409,628 |
| Sarepta Therapeutics(SRPT.US) | 0.14 | 736,792 |
| Mineralys Therapeutics(MLYS.US) | 0.14 | 420,513 |
| Zai Lab(ZLAB.US) | 0.14 | 625,373 |
| Nurix Therapeutics(NRIX.US) | 0.14 | 745,478 |
| Olema Pharmaceuticals(OLMA.US) | 0.13 | 472,835 |
| Arcus Biosciences(RCUS.US) | 0.13 | 559,176 |
| Recursion Pharmaceuticals(RXRX.US) | 0.13 | 3,092,732 |
| Kodiak Sciences(KOD.US) | 0.13 | 422,504 |
| Intellia Therapeutics(NTLA.US) | 0.13 | 819,680 |
| Novavax(NVAX.US) | 0.13 | 1,106,602 |
| Oruka Therapeutics(ORKA.US) | 0.12 | 317,662 |
| AnaptysBio(ANAB.US) | 0.12 | 193,902 |
| Nuvation Bio(NUVB.US) | 0.12 | 1,787,829 |
| Amylyx Pharmaceuticals(AMLX.US) | 0.12 | 678,478 |
| NovoCure(NVCR.US) | 0.12 | 747,529 |
| Relay Therapeutics(RLAY.US) | 0.11 | 968,659 |
| Biohaven(BHVN.US) | 0.11 | 832,946 |
| Iovance Biotherapeutics(IOVA.US) | 0.11 | 2,479,421 |
| Enliven Therapeutics(ELVN.US) | 0.11 | 322,040 |
| Galapagos(GLPG.US) | 0.11 | 280,282 |
| Immunocore(IMCR.US) | 0.10 | 285,851 |
| Tyra Biosciences(TYRA.US) | 0.10 | 271,161 |
| Maze Therapeutics(MAZE.US) | 0.10 | 194,139 |
| Corvus Pharmaceuticals(CRVS.US) | 0.10 | 473,297 |
| Mesoblast(MESO.US) | 0.09 | 516,204 |
| RAPT THERAPEUTICS INC | 0.09 | 133,793 |
| Geron(GERN.US) | 0.09 | 4,510,184 |
| Taysha Gene Therapies(TSHA.US) | 0.09 | 1,669,810 |
| Trevi Therapeutics(TRVI.US) | 0.09 | 629,511 |
| AtaiBeckley(ATAI.US) | 0.08 | 2,047,379 |
| Fortrea(FTRE.US) | 0.08 | 685,556 |
| Tango Therapeutics(TNGX.US) | 0.08 | 658,140 |
| MannKind(MNKD.US) | 0.08 | 2,224,377 |
| VENTYX BIOSCIENCES INC | 0.08 | 481,333 |
| Sionna Therapeutics(SION.US) | 0.08 | 181,593 |
| uniQure(QURE.US) | 0.08 | 422,913 |
| CareDx(CDNA.US) | 0.07 | 348,745 |
| Theravance Biopharma(TBPH.US) | 0.07 | 355,010 |
| MBX Biosciences(MBX.US) | 0.07 | 198,999 |
| Xencor(XNCR.US) | 0.07 | 503,997 |
| Vir Biotechnology(VIR.US) | 0.07 | 702,939 |
| Monte Rosa Therapeutics(GLUE.US) | 0.07 | 357,552 |
| Castle Biosciences(CSTL.US) | 0.07 | 213,665 |
| UroGen Pharma(URGN.US) | 0.07 | 290,156 |
| AbCellera Biologics(ABCL.US) | 0.07 | 1,732,734 |
| Rapport Therapeutics(RAPP.US) | 0.07 | 211,052 |
| Septerna(SEPN.US) | 0.07 | 201,907 |
| Day One Biopharmaceuticals(DAWN.US) | 0.07 | 552,603 |
| Stevanato Group(STVN.US) | 0.07 | 372,761 |
| Inhibrx Biosciences(INBX.US) | 0.06 | 76,450 |
| Pharvaris(PHVS.US) | 0.06 | 197,520 |
| Kura Oncology(KURA.US) | 0.06 | 633,801 |
| Arvinas(ARVN.US) | 0.06 | 415,393 |
| Janux Therapeutics(JANX.US) | 0.06 | 404,194 |
| Oric Pharmaceuticals(ORIC.US) | 0.06 | 403,015 |
| Arbutus Biopharma(ABUS.US) | 0.06 | 1,128,594 |
| Sana Biotechnology(SANA.US) | 0.06 | 1,246,437 |
| Annexon(ANNX.US) | 0.06 | 923,916 |
| CytomX Therapeutics(CTMX.US) | 0.06 | 960,717 |
| GH Research(GHRS.US) | 0.06 | 336,963 |
| BioAge Labs(BIOA.US) | 0.05 | 216,885 |
| KalVista Pharmaceuticals(KALV.US) | 0.05 | 283,886 |
| Savara(SVRA.US) | 0.05 | 767,766 |
| Rigel Pharmaceuticals(RIGL.US) | 0.05 | 132,764 |
| Cullinan Therapeutics(CGEM.US) | 0.05 | 296,235 |
| ArriVent Biopharma(AVBP.US) | 0.05 | 195,608 |
| Zenas BioPharma(ZBIO.US) | 0.05 | 164,791 |
| Phathom Pharmaceuticals(PHAT.US) | 0.05 | 340,621 |
| Precigen(PGEN.US) | 0.05 | 1,121,634 |
| ARS Pharma(SPRY.US) | 0.05 | 448,730 |
| Replimune Group(REPL.US) | 0.05 | 535,643 |
| Alto Neuroscience(ANRO.US) | 0.05 | 205,757 |
| Bicara Therapeutics(BCAX.US) | 0.05 | 240,974 |
| Ironwood Pharmaceuticals(IRWD.US) | 0.05 | 1,177,269 |
| Altimmune(ALT.US) | 0.05 | 933,700 |
| Cytek BioSciences(CTKB.US) | 0.04 | 870,813 |
| Rocket Pharmaceuticals(RCKT.US) | 0.04 | 748,270 |
| Zevra Therapeutics(ZVRA.US) | 0.04 | 419,567 |
| COMPASS Pathways(CMPS.US) | 0.04 | 541,186 |
| Perspective Therapeutics(CATX.US) | 0.04 | 691,476 |
| Vanda Pharmaceuticals(VNDA.US) | 0.04 | 413,860 |
| Fulcrum Therapeutics(FULC.US) | 0.04 | 438,770 |
| Personalis(PSNL.US) | 0.04 | 398,837 |
| Opko Health(OPK.US) | 0.04 | 2,943,569 |
| Pacific Biosciences of Californi(PACB.US) | 0.04 | 2,034,955 |
| Allogene Therapeutics(ALLO.US) | 0.04 | 1,197,976 |
| MeiraGTx Holdings(MGTX.US) | 0.04 | 437,916 |
| 4D Molecular Therapeutics(FDMT.US) | 0.04 | 340,277 |
| Alvotech(ALVO.US) | 0.04 | 820,277 |
| BridgeBio Oncology Therapeutics(BBOT.US) | 0.04 | 324,473 |
| Lexeo Therapeutics(LXEO.US) | 0.04 | 452,957 |
| Prime Medicine(PRME.US) | 0.04 | 704,903 |
| Lineage Cell Therapeutics(LCTX.US) | 0.04 | 1,634,294 |
| Standard BioTools(LAB.US) | 0.04 | 2,768,770 |
| REGENXBIO(RGNX.US) | 0.04 | 346,603 |
| Emergent Biosolutions(EBS.US) | 0.04 | 379,021 |
| Myriad Genetics(MYGN.US) | 0.03 | 666,370 |
| ADC Therapeutics(ADCT.US) | 0.03 | 746,149 |
| Keros Therapeutics(KROS.US) | 0.03 | 213,484 |
| Enanta Pharmaceuticals(ENTA.US) | 0.03 | 205,778 |
| Contineum Therapeutics(CTNM.US) | 0.03 | 188,102 |
| Anavex Life Sciences(AVXL.US) | 0.03 | 648,756 |
| Prothena(PRTA.US) | 0.03 | 326,028 |
| LENZ Therapeutics(LENZ.US) | 0.03 | 209,357 |
| Maravai LifeSciences(MRVI.US) | 0.03 | 793,768 |
| Absci(ABSI.US) | 0.03 | 1,019,704 |
| PepGen(PEPG.US) | 0.03 | 442,459 |
| Solid Biosciences(SLDB.US) | 0.03 | 442,699 |
| Design Therapeutics(DSGN.US) | 0.03 | 234,867 |
| Immutep(IMMP.US) | 0.03 | 846,248 |
| Autolus Therapeutics(AUTL.US) | 0.03 | 1,382,137 |
| Neurogene(NGNE.US) | 0.03 | 99,006 |
| Fulgent Genetics(FLGT.US) | 0.03 | 150,069 |
| Atea Pharmaceuticals(AVIR.US) | 0.02 | 463,499 |
| Kyverna Therapeutics(KYTX.US) | 0.02 | 262,747 |
| Ginkgo Bioworks(DNA.US) | 0.02 | 317,204 |
| Cabaletta Bio(CABA.US) | 0.02 | 634,415 |
| Aura Biosciences(AURA.US) | 0.02 | 353,572 |
| Aclaris Therapeutics(ACRS.US) | 0.02 | 695,071 |
| Entrada Therapeutics(TRDA.US) | 0.02 | 158,499 |
| Tectonic Therapeutic(TECX.US) | 0.02 | 79,365 |
| Larimar Therapeutics(LRMR.US) | 0.02 | 350,347 |
| NovaBridge(NBP.US) | 0.02 | 564,202 |
| Quanterix(QTRX.US) | 0.02 | 282,890 |
| Immuneering(IMRX.US) | 0.02 | 358,931 |
| Candel Therapeutics(CADL.US) | 0.02 | 308,503 |
| Arcturus Therapeutics(ARCT.US) | 0.02 | 195,503 |
| Editas Medicine(EDIT.US) | 0.02 | 729,320 |
| C4 Therapeutics(CCCC.US) | 0.02 | 583,123 |
| Atrium Therapeutics(RNA.US) | 0.02 | 101,552 |
| Upstream Bio(UPB.US) | 0.02 | 192,681 |
| Bicycle Therapeutics(BCYC.US) | 0.02 | 255,277 |
| Neumora Therapeutics(NMRA.US) | 0.02 | 409,301 |
| OmniAb(OABI.US) | 0.02 | 819,342 |
| Voyager Therapeutics(VYGR.US) | 0.02 | 344,091 |
| Cellectis(CLLS.US) | 0.02 | 355,405 |
| AC Immune(ACIU.US) | 0.02 | 463,722 |
| Humacyte(HUMA.US) | 0.02 | 1,187,272 |
| Lyell Immunopharma(LYEL.US) | 0.01 | 52,752 |
| Quantum-Si(QSI.US) | 0.01 | 1,279,502 |
| Caribou Biosciences(CRBU.US) | 0.01 | 621,676 |
| Aardvark Therapeutics(AARD.US) | 0.01 | 93,774 |
| Foghorn Therapeutics(FHTX.US) | 0.01 | 200,951 |
| Sagimet Biosciences(SGMT.US) | 0.01 | 197,855 |
